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・ Tumor Circus
・ Tumor hypoxia
・ Tumor initiation
・ Tumor lysis syndrome
・ Tumor M2-PK
・ Tumor marker
・ Tumor metabolome
・ Tumor microenvironment
・ Tumor necrosis factor alpha
・ Tumor necrosis factor receptor
・ Tumor necrosis factor receptor 1
・ Tumor necrosis factor receptor 2
・ Tumor necrosis factors
・ Tumor of the stomach
・ Tumor progression
Tumor promotion
・ Tumor reversion
・ Tumor suppressor gene
・ Tumor-associated calcium signal transducer
・ Tumor-associated glycoprotein
・ Tumor-associated glycoprotein 72
・ Tumor-associated macrophage
・ Tumor-induced osteomalacia
・ Tumor-infiltrating lymphocytes
・ Tumor-like disorders of the lung pleura
・ Tumoral calcinosis
・ Tumors of the hematopoietic and lymphoid tissues
・ Tumour heterogeneity
・ Tump
・ Tumpat


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Tumor promotion : ウィキペディア英語版
Tumor promotion
Tumor promotion is a process in carcinogenesis by which various factors permit the descendents of a single initiated cell to survive and expand in number, i.e. to resist apoptosis and to undergo clonal growth. This is a step toward tumor progression〔(【引用サイトリンク】title=NCI Dictionary of Cancer Terms:Tumor promotion )
In order for a tumor cell to survive, it must decrease its expression of tumor suppressor genes such as p53, BRCA1, BRCA2, RB1 or the fas receptor.〔(【引用サイトリンク】title=Oncogenes, Tumor Suppressor Genes,and Cancer )〕 A tumor suppressor would trigger an apoptotic pathway in a cancer cell if there were DNA damage, polyploidy, or uncontrolled cell growth.
Simultaneously, tumor cells need to upregulate oncogenes, which promote or cause downstream activation of growth factors and cell survival signals such as (Ras ), Mitogen-activated protein kinase kinase, VEGF, or Akt.〔(【引用サイトリンク】title=Oncogenes, Tumor Suppressor Genes,and Cancer )
==See also==

* Tumor progression
* Phorbol myristate acetate

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Tumor promotion」の詳細全文を読む



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